Which APP to measure?

This table is intended to help you decide which marker may be of help to you in assessing the acute phase response. The boxes on the grid that are not colour coded merely indicate that we have no data to support any recommendation.

Selection of Acute Phase Protein Assays In Various Species

 
Species Cp CRP Fib Hb LBP MAP SAA SAP a1-AGP a2-MG
                     
Cat                    
Cattle                    
Dog                    
Horse                    
Man/Monkey                    
Mouse                    
Pig                    
Rabbit                    
Rat                    
Sheep                    

 

  Major changes in the protein levels: TEST RECOMMENDED.
  Moderate to minor changes in the protein levels: THIS TEST MAY BE A USEFUL SECOND LINE TEST.
  No change in the protein levels: YOU ARE ADVISED NOT TO USE THIS TEST.

Abbreviations:

Cp = Ceruloplasmin; CRP = C-Reactive protein; Fib = Fibrinogen; Hb = Haptoglobin; LBP = Lipopolysaccharide Binding Protein; MAP = Major Acute-phase Protein; SAA = Serum Amyloid A; SAP = Serum Amyloid P; a1-AGP = a1-Acid Glycoprotein; a2-MG = a2-Macroglobulin